Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3924998 | 0.93 | DHODH (0.86) | DHODHNR4A2 | |
| SCHEMBL31326967 | 0.90 | DHODH (0.84) | DHODHNR4A2 | |
| SCHEMBL29868614 | 0.89 | DHODH (1.00) | DHODHNR4A2 | |
| SCHEMBL31326966 | 0.88 | DHODH (0.78) | DHODHNR4A2 | |
| SCHEMBL29868737 | 0.87 | DHODH (1.00) | DHODHNR4A2 | |
| SCHEMBL31125355 | 0.81 | DHODH (1.00) | DHODHNR4A2 | |
| SCHEMBL31026699 | 0.80 | DHODH (0.81) | DHODHNR4A2 | |
| SCHEMBL31326980 | 0.79 | DHODH (0.82) | DHODHNR4A2 | |
| SCHEMBL30511209 | 0.78 | DHODH (0.77) | DHODHNR4A2 | |
| Vidofludimus SCHEMBL29869156 | 0.78 | DHODH (1.00) | DHODHNR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250066290-A1 | DHODH INHIBITORS CONTAINING A CARBOXYLIC ACID BIOISOSTERE | IMMUNIC AG (DE) | 2025-02-27 | — | — | US | disclosed |
| CN-118382610-A | DHODH inhibitors containing carboxylic acid bioisosteres | 埃慕尼克股份公司 | 2024-07-23 | — | — | CN | disclosed |
| EP-4320100-A1 | DEUTERATED DHODH INHIBITORS | Immunic AG (DE) | 2024-02-14 | — | — | EP | disclosed |
| WO-2022214691-A1 | DEUTERATED DHODH INHIBITORS | IMMUNIC AG (DE) | 2022-10-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250066290-A1 | DHODH INHIBITORS CONTAINING A CARBOXYLIC ACID BIOISOSTERE | DHODH, DBH, DOHH | DHODH 1/4885NR4A2 2440/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.