SCHEMBL29868596

SCHEMBL29868596

CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O)[C@@H](C)O)C(C)C

nearest known ligand 0.69

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ CALCR P30988 5/20 0.69
▸ NPY2R P49146 8/20 0.68
▸ NPY4R P50391 8/20 0.68
▸ NPY5R Q15761 8/20 0.68
▸ NPY1R P25929 6/20 0.68
▸ RAMP1 O60894 1/20 0.66
▸ RAMP2 O60895 1/20 0.66
▸ RAMP3 O60896 1/20 0.66
▸ CALCRL Q16602 1/20 0.66
▸ TFPI P10646 2/20 0.64
▸ KDM1A O60341 1/20 0.63
▸ CCKBR P32239 2/20 0.63
▸ GLP1R P43220 2/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29868686 0.95 NPY2R (0.68) CALCRNPY2RNPY4RNPY5RNPY1R
SCHEMBL29496288 0.92 NPY2R (0.74) CALCRNPY2RNPY4RNPY5RNPY1R
SCHEMBL31744322 0.91 CALCR (0.77) CALCRNPY2RNPY4RNPY5RNPY1R
SCHEMBL13248707 0.91 NPY2R (0.80) CALCRNPY2RNPY4RNPY5RNPY1R
SCHEMBL31464902 0.90 CALCR (0.69) CALCRRAMP1RAMP2RAMP3CALCRL
SCHEMBL31464899 0.90 CALCR (0.69) CALCRRAMP1RAMP2RAMP3CALCRL
SCHEMBL30001479 0.90 CALCR (0.80) CALCRNPY2RNPY4RNPY5RNPY1R
SCHEMBL30001037 0.90 CALCR (0.78) CALCRNPY2RNPY4RNPY5RNPY1R
SCHEMBL30422726 0.90 CALCR (0.71) CALCRRAMP1RAMP2RAMP3CALCRL
SCHEMBL30495769 0.90 MAPK8 (0.69) CALCRNPY2RNPY4RNPY5RNPY1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3720872-B1 ANALOGUES OF PYY IP2IPO INNOVATIONS LTD (GB) 2026-03-25 — — EP claimed
CN-111727198-B Pyy analogues IP2IPO创新有限公司 2024-07-09 — — CN claimed
US-12617830-B2 Analogues of PYY IP2IPO INNOVATIONS LIMITED (GB) 2026-05-05 — — US disclosed
EP-3720872-B1 ANALOGUES OF PYY IP2IPO INNOVATIONS LTD (GB) 2026-03-25 — — EP disclosed
US-12060402-B2 Analogues of PYY IP2IPO INNOVATIONS LIMITED (GB) 2024-08-13 — — US disclosed
CN-111727198-B Pyy analogues IP2IPO创新有限公司 2024-07-09 — — CN disclosed
US-20240166709-A1 ANALOGUES OF PYY IP2IPO INNOVATIONS LIMITED (GB) 2024-05-23 — — US disclosed
US-20230126347-A1 ANALOGUES OF PYY IP2IPO INNOVATIONS LIMITED (GB) 2023-04-27 — — US disclosed
US-11421012-B2 Analogues of PYY IP2IPO INNOVATIONS LIMITED (GB) 2022-08-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12617830-B2 Analogues of PYY GLP1R, INSR, GIPR CALCR 1972/4885NPY2R 31/4885NPY4R 22/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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