Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 19/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 18/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29603662 | 0.80 | GRIN1 (0.44) | GRIN2BGRIN1KCNH2 | |
| SCHEMBL17520438 | 0.76 | GRIN2B (0.54) | GRIN2BGRIN1KCNH2 | |
| SCHEMBL29604388 | 0.76 | GRIN1 (0.46) | GRIN2BGRIN1 | |
| SCHEMBL22775638 | 0.76 | GRIN1 (0.53) | GRIN2BGRIN1 | |
| SCHEMBL22770996 | 0.76 | GRIN1 (0.51) | GRIN2BGRIN1 | |
| SCHEMBL22770894 | 0.76 | GRIN1 (0.46) | GRIN2BGRIN1 | |
| SCHEMBL22770858 | 0.76 | GRIN1 (0.48) | GRIN2BGRIN1 | |
| SCHEMBL22771420 | 0.75 | GRIN2B (0.55) | GRIN2BGRIN1KCNH2 | |
| SCHEMBL22787203 | 0.75 | GRIN1 (0.50) | GRIN2BGRIN1 | |
| SCHEMBL30112658 | 0.74 | GRIN2B (0.52) | GRIN2BGRIN1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11447503-B2 | Pyridine carbamates and their use as GLUN2B receptor modulators | JANSSEN PHARMACEUTICA NV (BE) | 2022-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11447503-B2 | Pyridine carbamates and their use as GLUN2B receptor modulators | GRIN2B, GRIN2A, GRIN1 | GRIN2B 1/4885GRIN1 3/4885KCNH2 1849/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.