Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | KLK7 | P49862 | 2/20 | 0.51 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.49 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18123350 | 0.95 | SYK (0.79) | SYKMAPTKLK7KLK5ATM | |
| SCHEMBL16286152 | 0.93 | SYK (0.69) | SYKMAPTKLK7KLK5ATM | |
| Bicarbonate SCHEMBL5175781 | 0.91 | MAPT (0.66) | SYKMAPTKLK7KLK5HTT | |
| SCHEMBL6620803 | 0.91 | SYK (0.61) | SYKMAPTKLK7KLK5ATM | |
| SCHEMBL6619895 | 0.91 | SYK (0.61) | SYKMAPTKLK7KLK5ATM | |
| SCHEMBL6620798 | 0.91 | SYK (0.61) | SYKMAPTKLK7KLK5ATM | |
| SCHEMBL19295602 | 0.90 | SYK (0.73) | SYKMAPTKLK7KLK5ATM | |
| SCHEMBL19295572 | 0.90 | SYK (0.60) | SYKMAPTKLK7KLK5ATM | |
| SCHEMBL6372825 | 0.90 | SYK (0.60) | SYKMAPTKLK7KLK5ATM | |
| SCHEMBL6372820 | 0.90 | SYK (0.60) | SYKMAPTKLK7KLK5ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115210237-B | Dihydropyrimidine compound, preparation method and application thereof | 上海维申医药有限公司 | 2023-11-14 | — | — | CN | disclosed |
| CN-114907355-A | Dihydropyrimidine compound, preparation method and application thereof | 上海维申医药有限公司 | 2022-08-16 | — | — | CN | disclosed |