Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 20/20 | 0.53 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.49 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28864701 | 1.00 | MET (0.53) | METPDGFRBPDGFRAKDR | |
| SCHEMBL29870110 | 0.85 | MET (0.73) | METPDGFRBPDGFRAKDR | |
| SCHEMBL28864667 | 0.85 | MET (0.73) | METPDGFRBPDGFRAKDR | |
| SCHEMBL28864748 | 0.81 | MET (0.47) | METPDGFRBPDGFRAKDR | |
| SCHEMBL29870088 | 0.81 | MET (0.47) | METPDGFRBPDGFRAKDR | |
| SCHEMBL29870295 | 0.72 | MET (0.71) | METPDGFRBPDGFRAKDR | |
| SCHEMBL28956734 | 0.72 | MET (0.71) | METPDGFRBPDGFRAKDR | |
| SCHEMBL28864709 | 0.72 | MET (0.77) | METPDGFRBPDGFRAKDR | |
| SCHEMBL975832 | 0.70 | CDK2 (0.44) | MET | |
| SCHEMBL28864703 | 0.70 | MET (0.74) | METPDGFRBPDGFRAKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107312009-B | Quinoline compound, preparation method, intermediate, pharmaceutical composition and application thereof | 上海医药集团股份有限公司 | 2022-09-20 | — | — | CN | disclosed |