SCHEMBL29869780

SCHEMBL29869780

Brc1cnc2nnn(Cc3ccc4ncccc4c3)c2n1

nearest known ligand 0.76

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MET P08581 20/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1163320 1.00 MET (0.76) MET
SCHEMBL12165479 0.87 MET (0.77) MET
SCHEMBL2575337 0.86 MET (1.00) MET
SCHEMBL2573410 0.86 MET (1.00) MET
SCHEMBL2574456 0.85 MET (0.75) MET
SCHEMBL6522746 0.85 MET (0.55) MET
SCHEMBL29869671 0.85 MET (0.55) MET
SCHEMBL2573763 0.84 MET (0.76) MET
SCHEMBL2573179 0.84 MET (1.00) MET
SCHEMBL2571930 0.84 MET (0.64) MET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113412112-B Organophosphorus substituted compounds as c-MET inhibitors and therapeutic uses thereof 贝达医药公司 2024-06-11 CN disclosed
CN-107312009-B Quinoline compound, preparation method, intermediate, pharmaceutical composition and application thereof 上海医药集团股份有限公司 2022-09-20 CN disclosed