Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 20/20 | 0.76 |
| ▸ | KIT | P10721 | 1/20 | 0.49 |
| ▸ | SRC | P12931 | 1/20 | 0.49 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.49 |
| ▸ | AXL | P30530 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | MST1R | Q04912 | 1/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29869906 | 0.86 | MET (0.75) | METKITSRCPDGFRAAXL | |
| SCHEMBL29869972 | 0.85 | MET (0.76) | METKITSRCPDGFRAAXL | |
| SCHEMBL29870161 | 0.85 | MET (0.77) | METKITSRCPDGFRAAXL | |
| SCHEMBL29869838 | 0.84 | MET (0.83) | METKITSRCPDGFRAAXL | |
| SCHEMBL29870326 | 0.83 | MET (0.86) | METKITSRCPDGFRAAXL | |
| SCHEMBL29869650 | 0.83 | MET (0.79) | METKITSRCPDGFRAAXL | |
| SCHEMBL29869814 | 0.83 | MET (0.79) | METKITSRCPDGFRAAXL | |
| SCHEMBL29869799 | 0.83 | MET (0.76) | METKITSRCPDGFRAAXL | |
| SCHEMBL29870042 | 0.83 | MET (0.85) | METKITSRCPDGFRAAXL | |
| SCHEMBL29869956 | 0.81 | MET (0.82) | METKITSRCPDGFRAAXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107312009-B | Quinoline compound, preparation method, intermediate, pharmaceutical composition and application thereof | 上海医药集团股份有限公司 | 2022-09-20 | — | — | CN | disclosed |