Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.59 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | NPEPPS | P55786 | 6/20 | 0.52 |
| ▸ | SLC29A1 | Q99808 | 5/20 | 0.52 |
| ▸ | STAT6 | P42226 | 1/20 | 0.50 |
| ▸ | ANPEP | P15144 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | NPY1R | P25929 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPY2R | P49146 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29870652 | 0.90 | LMNA (0.59) | LMNAADORA2AADORA2BCYP1A2NPEPPS | |
| SCHEMBL15948768 | 0.84 | ADORA2A (0.56) | ADORA2AADORA2BNPEPPSSLC29A1STAT6 | |
| SCHEMBL31160178 | 0.84 | LMNA (0.79) | LMNAADORA2AADORA2BCYP1A2NPEPPS | |
| SCHEMBL29793020 | 0.82 | TYMP (0.57) | LMNAADORA1 | |
| SCHEMBL23579255 | 0.81 | LMNA (0.51) | LMNAADORA2AADORA2BCYP1A2NPEPPS | |
| SCHEMBL29870665 | 0.81 | LMNA (0.51) | LMNAADORA2AADORA2BCYP1A2NPEPPS | |
| SCHEMBL21625242 | 0.80 | LMNA (0.60) | LMNAADORA2AADORA2BCYP1A2SLC29A1 | |
| SCHEMBL314050 | 0.80 | LMNA (0.60) | LMNAADORA2AADORA2BCYP1A2SLC29A1 | |
| SCHEMBL20482906 | 0.80 | LMNA (0.64) | LMNAADORA2AADORA2BCYP1A2NPEPPS | |
| SCHEMBL21063207 | 0.80 | LMNA (0.60) | LMNAADORA2AADORA2BCYP1A2SLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117769598-A | Polynucleotide and pharmaceutical composition | 协和麒麟株式会社 | 2024-03-26 | — | — | CN | disclosed |
| CN-115176000-A | Polynucleotide and pharmaceutical composition | 国立大学法人东海国立大学机构 | 2022-10-11 | — | — | CN | disclosed |