Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CTSV | O60911 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RHEB | Q15382 | 1/20 | 0.39 |
| ▸ | FOXM1 | Q08050 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26428048 | 1.00 | MAOB (0.43) | MAOBTDP1KDM4EMAPK1ALOX5 | |
| SCHEMBL8220968 | 0.88 | MAOB (0.43) | MAOBTDP1KDM4EMAPK1ALOX5 | |
| SCHEMBL30065009 | 0.86 | MAOB (0.57) | MAOBALOX5MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL8251097 | 0.86 | MAOB (0.57) | MAOBALOX5MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL27443252 | 0.82 | TSHR (0.42) | MAOBTDP1KDM4EMAPK1ALOX5 | |
| SCHEMBL13862125 | 0.79 | MAOB (0.43) | MAOBTDP1KDM4EMAPK1ALOX5 | |
| SCHEMBL34465802 | 0.79 | MAOB (0.43) | MAOBTDP1KDM4EMAPK1ALOX5 | |
| SCHEMBL5936645 | 0.79 | MEN1 (0.53) | MAOBTDP1KDM4EMAPK1ALOX5 | |
| SCHEMBL3120643 | 0.79 | TSHR (0.50) | MAOBNPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL3445766 | 0.79 | MAOB (0.43) | MAOBTDP1KDM4EMAPK1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4110777-A1 | PYRROLOPYRIDINE AND IMIDAZOPYRIDINE ANTIVIRAL COMPOUNDS | Katholieke Universiteit Leuven, K.U.Leuven R&D (BE) | 2023-01-04 | — | — | EP | disclosed |
| CN-115175909-A | Pyrrolopyridine and imidazopyridine antiviral compounds | 鲁汶天主教大学 | 2022-10-11 | — | — | CN | disclosed |