Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4170449 | 0.93 | MEN1 (0.52) | MEN1KMT2APOLBNPC1RAB9A | |
| SCHEMBL749857 | 0.86 | MEN1 (0.59) | MEN1KMT2APOLBNPC1RAB9A | |
| SCHEMBL214564 | 0.85 | RAB9A (0.46) | NPC1RAB9ASMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL34465802 | 0.82 | MAOB (0.43) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8220968 | 0.82 | MAOB (0.43) | NPC1RAB9ASMN1; SMN2TDP1MAPT | |
| SCHEMBL1870380 | 0.82 | MEN1 (0.59) | MEN1KMT2APOLBNPC1RAB9A | |
| SCHEMBL4163135 | 0.80 | S1PR1 (0.46) | TDP1L3MBTL1MAOBKDM4EMAPK1 | |
| SCHEMBL17669520 | 0.80 | NCF1 (0.48) | MEN1KMT2APOLBNPC1RAB9A | |
| SCHEMBL29870987 | 0.79 | MAOB (0.43) | NPC1RAB9ASMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL26428048 | 0.79 | MAOB (0.43) | NPC1RAB9ASMN1; SMN2TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060035844-A1 | Preventive or remedy for diseases caused by hyperglycemia | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2006-02-16 | — | — | US | disclosed |
| EP-1568380-A1 | PREVENTIVE OR REMEDY FOR DISEASES CAUSED BY HYPERGLYCEMIA | Kissei Pharmaceutical Co., Ltd. (JP) | 2005-08-31 | — | — | EP | disclosed |