Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE1B | Q01064 | 7/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | NPBWR1 | P48145 | 3/20 | 0.38 |
| ▸ | PDE1A | P54750 | 1/20 | 0.38 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29872467 | 0.86 | ALDH1A1 (0.46) | PDE1BLMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL1593023 | 0.82 | CNR1 (0.47) | PDE1BLMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL29873266 | 0.82 | MAPT (0.45) | PDE1BMAPTSMN1; SMN2CNR1CNR2 | |
| SCHEMBL1593160 | 0.81 | MAPT (0.43) | PDE1BLMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL1593142 | 0.80 | CNR1 (0.47) | PDE1BLMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL1594020 | 0.78 | CNR1 (0.46) | PDE1BLMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL29873567 | 0.76 | MAPT (0.44) | LMNAMAPTALDH1A1SMN1; SMN2ALOX15 | |
| SCHEMBL16536772 | 0.75 | PDE1B (0.53) | PDE1BLMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL4935801 | 0.75 | CNR1 (0.43) | PDE1BLMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL1593833 | 0.74 | CNR2 (0.42) | PDE1BLMNAMAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220306640-A1 | HYDANTOIN DERIVATIVE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2022-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220306640-A1 | HYDANTOIN DERIVATIVE | DDR1, DDR2, DDRGK1 | PDE1B 1600/4885LMNA 1274/4885MAPT 3943/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.