Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 11/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 3/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19926333 | 1.00 | MAT2A (0.47) | MAT2AKDM1AKITPDE2APIK3CA | |
| SCHEMBL21215550 | 0.94 | KDM1A (0.41) | MAT2AKDM1AKITPDE2APIK3CA | |
| SCHEMBL29875148 | 0.87 | MAT2A (0.52) | MAT2AALDH1A1 | |
| SCHEMBL19926981 | 0.87 | MAT2A (0.52) | MAT2AALDH1A1 | |
| SCHEMBL19926567 | 0.87 | MAT2A (0.52) | MAT2AALDH1A1MEN1HTTKMT2A | |
| SCHEMBL19936241 | 0.86 | MAT2A (0.56) | MAT2AALDH1A1MEN1HTTKMT2A | |
| SCHEMBL19972128 | 0.85 | MAT2A (0.49) | MAT2AKITPDE2APIK3CDMEN1 | |
| SCHEMBL29875410 | 0.85 | MAT2A (0.49) | MAT2AKITPDE2APIK3CDMEN1 | |
| SCHEMBL19926850 | 0.83 | MAT2A (0.52) | MAT2AALDH1A1 | |
| SCHEMBL19927671 | 0.83 | MAT2A (0.53) | MAT2AALDH1A1MEN1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109890822-B | Inhibitors of cellular metabolic processes | 安吉奥斯医药品有限公司 | 2022-08-30 | — | — | CN | disclosed |