Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 14/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19926006 | 1.00 | MAT2A (0.52) | MAT2ABRD4CREBBPALDH1A1ADORA2A | |
| SCHEMBL19927671 | 0.90 | MAT2A (0.53) | MAT2AALDH1A1 | |
| SCHEMBL19936241 | 0.90 | MAT2A (0.56) | MAT2AALDH1A1 | |
| SCHEMBL19926739 | 0.89 | MAT2A (0.48) | MAT2AALDH1A1 | |
| SCHEMBL19972078 | 0.86 | MAT2A (0.52) | MAT2AALDH1A1 | |
| SCHEMBL19972068 | 0.85 | MAT2A (0.52) | MAT2AALDH1A1 | |
| SCHEMBL19926860 | 0.85 | MAT2A (0.51) | MAT2AALDH1A1 | |
| SCHEMBL19927037 | 0.84 | MAT2A (0.66) | MAT2AALDH1A1 | |
| SCHEMBL19926347 | 0.84 | MAT2A (0.44) | MAT2AALDH1A1 | |
| SCHEMBL19926494 | 0.84 | MAT2A (0.47) | MAT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109890822-B | Inhibitors of cellular metabolic processes | 安吉奥斯医药品有限公司 | 2022-08-30 | — | — | CN | disclosed |