Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18128716 | 1.00 | KDM4E (0.31) | KDM4EMEN1ALDH1A1GAAMAPT | |
| SCHEMBL19104274 | 0.88 | KDM4E (0.30) | KDM4EMEN1ALDH1A1GAAMAPT | |
| SCHEMBL18153428 | 0.86 | MAPK14 (0.36) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL18128520 | 0.77 | ALDH1A1 (0.31) | ALDH1A1KMT2A | |
| SCHEMBL29654262 | 0.77 | ALDH1A1 (0.31) | ALDH1A1KMT2A | |
| SCHEMBL30101999 | 0.76 | — | — | |
| SCHEMBL22029169 | 0.76 | — | — | |
| SCHEMBL25805402 | 0.75 | MEN1 (0.37) | KDM4EMEN1ALDH1A1GAAMAPT | |
| SCHEMBL25382988 | 0.75 | KRAS (0.36) | KDM4EALDH1A1GAA | |
| SCHEMBL20571102 | 0.75 | MAP3K8 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116867779-A | KRAS inhibitors for cancer treatment | 泰励生物科技（上海）有限公司 | 2023-10-10 | — | — | CN | disclosed |
| CN-114920738-A | KRas inhibitors for cancer treatment | 泰励生物科技（上海）有限公司 | 2022-08-19 | — | — | CN | disclosed |