Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETD2 | Q9BYW2 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | PRCP | P42785 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29876794 | 1.00 | SETD2 (0.37) | SETD2SMN1; SMN2L3MBTL1EPHX2L3MBTL3 | |
| SCHEMBL2723003 | 0.88 | KDM1A (0.43) | SETD2SMN1; SMN2L3MBTL1EPHX2L3MBTL3 | |
| SCHEMBL20478065 | 0.88 | KDM1A (0.43) | SETD2SMN1; SMN2L3MBTL1EPHX2L3MBTL3 | |
| SCHEMBL2696030 | 0.88 | KDM1A (0.43) | SETD2SMN1; SMN2L3MBTL1EPHX2L3MBTL3 | |
| SCHEMBL2696025 | 0.88 | KDM1A (0.43) | SETD2SMN1; SMN2L3MBTL1EPHX2L3MBTL3 | |
| SCHEMBL3767054 | 0.88 | KDM1A (0.43) | SETD2SMN1; SMN2L3MBTL1EPHX2L3MBTL3 | |
| SCHEMBL20478066 | 0.88 | KDM1A (0.43) | SETD2SMN1; SMN2L3MBTL1EPHX2L3MBTL3 | |
| SCHEMBL854180 | 0.84 | PDE7A (0.46) | SMN1; SMN2L3MBTL1EPHX2L3MBTL3KDM1A | |
| SCHEMBL854179 | 0.84 | PDE7A (0.46) | SMN1; SMN2L3MBTL1EPHX2L3MBTL3KDM1A | |
| SCHEMBL4167604 | 0.82 | SIGMAR1 (0.39) | L3MBTL1L3MBTL3ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022194237-A1 | QUINOLINE DERIVATIVE AND APPLICATION THEREOF IN PREPARATION OF AUTOIMMUNE DRUG | 成都百裕制药股份有限公司 | 2022-09-22 | — | — | WO | disclosed |