Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 10/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.60 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MLYCD | O95822 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16211302 | 0.95 | HDAC1 (0.66) | HDAC6HDAC1HDAC8HDAC5GAA | |
| SCHEMBL16211548 | 0.94 | HDAC6 (0.67) | HDAC6HDAC1HDAC8HDAC5HDAC11 | |
| SCHEMBL30493918 | 0.94 | HDAC6 (0.67) | HDAC6HDAC1HDAC8HDAC5HDAC11 | |
| SCHEMBL22217910 | 0.87 | HDAC6 (0.67) | HDAC6HDAC1HDAC8HDAC5HDAC11 | |
| SCHEMBL25979367 | 0.86 | HDAC6 (0.64) | HDAC6HDAC1HDAC8HDAC5HDAC11 | |
| SCHEMBL16211284 | 0.86 | HDAC1 (0.54) | HDAC6HDAC1HDAC8HDAC5HPGD | |
| SCHEMBL16211664 | 0.86 | MLYCD (0.57) | HDAC6HDAC1HDAC8GAAMLYCD | |
| SCHEMBL16211278 | 0.85 | HDAC1 (0.57) | HDAC6HDAC1HDAC8HDAC5GAA | |
| SCHEMBL16211327 | 0.85 | HDAC6 (0.53) | HDAC6HDAC1HDAC8HDAC5NR1H4 | |
| SCHEMBL16211461 | 0.85 | HDAC6 (0.58) | HDAC6HDAC1HDAC8HDAC5HDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4048280-A1 | COMPOSITIONS FOR PREVENTING OR TREATING CHRONIC OBSTRUCTIVE PULMONARY DISEASES (COPD) | Chong Kun Dang Pharmaceutical Corp. (KR) | 2022-08-31 | — | — | EP | disclosed |