SCHEMBL29880253

CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(=O)O)NC(=O)CNC(=O)[C@@H](N)Cc1c[nH]cn1)[C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	CALCR	P30988	4/20	0.59

▸	CRHR1	P34998	1/20	0.57

▸	CRHR2	Q13324	1/20	0.57

▸	GLP1R	P43220	8/20	0.56

▸	KEAP1	Q14145	1/20	0.55

▸	F2	P00734	4/20	0.55

▸	PTH1R	Q03431	1/20	0.53

▸	CCKBR	P32239	1/20	0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31243560	0.97	CALCR (0.59)	CALCRCRHR1CRHR2GLP1RKEAP1
SCHEMBL30504295	0.92	CALCR (0.52)	CALCRCRHR1CRHR2GLP1RKEAP1
SCHEMBL31441459	0.92	KEAP1 (0.65)	GLP1RKEAP1CCKBR
SCHEMBL30956314	0.91	CALCR (0.50)	CALCRCRHR1CRHR2GLP1RKEAP1
SCHEMBL30956313	0.91	CALCR (0.50)	CALCRCRHR1CRHR2GLP1RKEAP1
SCHEMBL30778184	0.90	CALCR (0.60)	CALCRCRHR1CRHR2GLP1RPTH1R
SCHEMBL29880436	0.90	CALCR (0.60)	CALCRCRHR1CRHR2GLP1RPTH1R
SCHEMBL29726691	0.90	CALCR (0.60)	CALCRCRHR1CRHR2GLP1RPTH1R
SCHEMBL31243563	0.89	GLP1R (0.60)	GLP1R
SCHEMBL29616372	0.89	GLP1R (0.56)	GLP1RF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20260116928-A1	COMPOSITIONS AND PARTICLES FOR PAYLOAD DELIVERY	THORNHILL THERAPEUTICS INC (US)	2026-04-30	—	—	US	disclosed
US-20220275029-A1	COMPOSITIONS AND PARTICLES FOR PAYLOAD DELIVERY	THORNHILL THERAPEUTICS, INC.	2022-09-01	—	—	US	disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

Patent	Title	Text reads most about	Predicted target · text-rank
US-20260116928-A1	COMPOSITIONS AND PARTICLES FOR PAYLOAD DELIVERY	SLC47A2, SLC47A1, SLC39A14	CALCR 374/4885CRHR1 1608/4885CRHR2 1141/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.