Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.58 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.53 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.52 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HPGDS | O60760 | 1/20 | 0.48 |
| ▸ | SPR | P35270 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31566742 | 1.00 | PDE4B (0.58) | PDE4BHSD11B1GPR119USP30TP53 | |
| SCHEMBL26667052 | 0.93 | PDE4B (0.52) | PDE4BHSD11B1GPR119USP30LMNA | |
| SCHEMBL25343613 | 0.93 | PDE4B (0.52) | PDE4BHSD11B1GPR119USP30LMNA | |
| SCHEMBL1854582 | 0.92 | GPR119 (0.57) | GPR119NAMPTLMNAKDM4EMAPT | |
| SCHEMBL8120252 | 0.89 | GPR119 (0.47) | PDE4BGPR119USP30KDM4E | |
| SCHEMBL6950631 | 0.87 | GPR119 (0.53) | GPR119NAMPTLMNAKDM4EMAPT | |
| SCHEMBL1751432 | 0.86 | TP53 (0.59) | PDE4BGPR119USP30TP53NAMPT | |
| SCHEMBL697513 | 0.86 | TP53 (0.59) | PDE4BGPR119USP30TP53NAMPT | |
| SCHEMBL23951735 | 0.86 | TP53 (0.59) | PDE4BGPR119USP30TP53NAMPT | |
| SCHEMBL23060497 | 0.85 | PDE4B (0.64) | PDE4BHSD11B1GPR119NAMPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025096637-A1 | SUBSTITUTED ARYL SULFONAMIDES FOR USE AS SODIUM CHANNEL INHIBITORS | XENON PHARMACEUTICALS INC. (CA) | 2025-05-08 | — | — | WO | disclosed |
| CN-115103709-A | MASP-2 inhibitors and methods of use | 奥默罗斯公司 | 2022-09-23 | — | — | CN | disclosed |