Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | EDNRA | P25101 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3571809 | 1.00 | RORC (0.43) | RORCUSP2ALPGMEN1KMT2A | |
| SCHEMBL3570731 | 0.89 | RORC (0.48) | RORCUSP2ALPGMEN1KMT2A | |
| SCHEMBL29881284 | 0.89 | RORC (0.48) | RORCUSP2ALPGMEN1KMT2A | |
| SCHEMBL3566327 | 0.87 | HCRTR1 (0.43) | MEN1KMT2ASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL3564525 | 0.87 | SMN1; SMN2 (0.40) | MEN1KMT2AHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL3560978 | 0.85 | HCRTR1 (0.45) | ALPGMEN1KMT2AHPGDHTT | |
| SCHEMBL3564261 | 0.83 | MEN1 (0.42) | MEN1KMT2AHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL3567092 | 0.82 | USP2 (0.45) | USP2ALPGMEN1KMT2AEDNRA | |
| SCHEMBL3566382 | 0.81 | MEN1 (0.41) | MEN1KMT2ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL28819508 | 0.77 | HCRTR1 (0.37) | MEN1KMT2ASMN1; SMN2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110404073-B | Methods and pharmaceutical compositions for treating hepatitis B virus infection | 国家医疗保健研究所 | 2022-08-16 | — | — | CN | disclosed |