Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 3/20 | 0.57 |
| ▸ | LIPE | Q05469 | 8/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | LPL | P06858 | 2/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1892366 | 1.00 | LIPG (0.57) | LIPGLIPENR1H4ENPP2LPL | |
| SCHEMBL29881417 | 0.90 | LIPG (0.57) | LIPGLIPEENPP2LPLHSD11B1 | |
| SCHEMBL29880608 | 0.90 | LIPG (0.57) | LIPGLIPELPLHSD11B1 | |
| SCHEMBL1887869 | 0.90 | LIPG (0.57) | LIPGLIPEENPP2LPLHSD11B1 | |
| SCHEMBL1884656 | 0.90 | LIPG (0.57) | LIPGLIPELPLHSD11B1 | |
| SCHEMBL16354309 | 0.88 | LIPG (0.54) | LIPGLIPEENPP2LPLHCRTR1 | |
| SCHEMBL16354158 | 0.78 | LIPG (0.54) | LIPGLIPEENPP2LPLHSD11B1 | |
| SCHEMBL16354256 | 0.78 | LIPG (0.54) | LIPGLIPEENPP2LPLHSD11B1 | |
| SCHEMBL1890094 | 0.76 | LIPG (0.49) | LIPGLIPELPL | |
| SCHEMBL1887486 | 0.73 | EPHX2 (0.44) | LIPGNR1H4LPLTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110404073-B | Methods and pharmaceutical compositions for treating hepatitis B virus infection | 国家医疗保健研究所 | 2022-08-16 | — | — | CN | disclosed |