Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 17/20 | 0.43 |
| ▸ | JAK1 | P23458 | 13/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29882985 | 0.88 | TYK2 (0.48) | TYK2JAK1KCNH2STAT3 | |
| SCHEMBL29883074 | 0.82 | TYK2 (0.52) | TYK2JAK1KCNH2 | |
| SCHEMBL29883000 | 0.82 | TYK2 (0.60) | TYK2JAK1KCNH2STAT3 | |
| SCHEMBL29232107 | 0.82 | AXL (0.51) | TYK2JAK1KCNH2 | |
| SCHEMBL30636426 | 0.80 | TYK2 (0.45) | TYK2JAK1PLK1MAPT | |
| SCHEMBL29882789 | 0.80 | TYK2 (0.61) | TYK2JAK1KCNH2STAT3 | |
| SCHEMBL29883118 | 0.79 | JAK1 (0.45) | TYK2JAK1KCNH2STAT3 | |
| SCHEMBL29232093 | 0.79 | JAK1 (0.45) | TYK2JAK1KCNH2STAT3 | |
| SCHEMBL25712180 | 0.78 | TYK2 (0.57) | TYK2JAK1KCNH2 | |
| SCHEMBL25712182 | 0.78 | TYK2 (0.59) | TYK2JAK1KCNH2STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115197196-B | TYK2 inhibitor and application thereof | 扬子江药业集团有限公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-115197196-A | TYK2 inhibitor and application thereof | 扬子江药业集团有限公司 | 2022-10-18 | — | — | CN | disclosed |