Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.56 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.51 |
| ▸ | PDE4A | P27815 | 5/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.51 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29174154 | 1.00 | TNF (0.60) | TNFPOLBKEAP1NFE2L2SMN1; SMN2 | |
| SCHEMBL9115691 | 0.94 | TNF (0.58) | TNFPOLBKEAP1NFE2L2SMN1; SMN2 | |
| SCHEMBL7183447 | 0.90 | PDE4A (0.64) | TNFPOLBKEAP1NFE2L2SMN1; SMN2 | |
| SCHEMBL29184115 | 0.89 | TNF (0.59) | TNFPOLBSMN1; SMN2PDE4DPDE4A | |
| SCHEMBL27702960 | 0.88 | GAA (0.52) | TNFPOLBKEAP1NFE2L2SMN1; SMN2 | |
| SCHEMBL12635172 | 0.86 | TNF (0.52) | TNFPOLBKEAP1NFE2L2SMN1; SMN2 | |
| SCHEMBL6885590 | 0.85 | PDE4A (0.71) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL29184126 | 0.84 | POLB (0.52) | TNFPOLBSMN1; SMN2PDE4DPDE4A | |
| SCHEMBL4823564 | 0.83 | PDE4D (0.57) | TNFPOLBPDE4DPDE4APDE4B | |
| SCHEMBL2890299 | 0.83 | TNF (0.47) | TNFPOLBSMN1; SMN2PDE4DPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115197036-B | Method for performing anti-mahalanobis hydrogen carboxylation reaction on photocatalytic olefin compound and carbon dioxide | 中国科学院理化技术研究所 | 2024-01-23 | — | — | CN | disclosed |
| CN-115197036-A | Method for carrying out anti-Ma hydrocarboxylation reaction on olefin compound and carbon dioxide by photocatalysis | 中国科学院理化技术研究所 | 2022-10-18 | — | — | CN | disclosed |