Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 4/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.48 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | NTSR1 | P30989 | 4/20 | 0.46 |
| ▸ | GRB2 | P62993 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.44 |
| ▸ | OXTR | P30559 | 1/20 | 0.44 |
| ▸ | FLT1 | P17948 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | CIB1 | Q99828 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29773696 | 1.00 | KRAS (0.49) | KRASHDAC4PLGNTSR1GRB2 | |
| SCHEMBL29773704 | 1.00 | KRAS (0.49) | KRASHDAC4PLGNTSR1GRB2 | |
| SCHEMBL29390495 | 1.00 | KRAS (0.49) | KRASHDAC4PLGNTSR1GRB2 | |
| SCHEMBL29773756 | 0.97 | PLG (0.51) | KRASHDAC4PLGNTSR1HDAC3 | |
| SCHEMBL29884584 | 0.94 | KRAS (0.47) | KRASHDAC4PLGNTSR1GRB2 | |
| SCHEMBL30928172 | 0.94 | PLG (0.49) | KRASHDAC4PLGNTSR1GRB2 | |
| SCHEMBL29740322 | 0.94 | PLG (0.49) | KRASHDAC4PLGNTSR1GRB2 | |
| SCHEMBL21303808 | 0.94 | PLG (0.49) | KRASHDAC4PLGNTSR1GRB2 | |
| SCHEMBL29884013 | 0.94 | PLG (0.49) | KRASHDAC4PLGNTSR1GRB2 | |
| SCHEMBL29773718 | 0.94 | PLG (0.49) | KRASHDAC4PLGNTSR1GRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11421223-B2 | Processes and host cells for genome, pathway, and biomolecular engineering | ENEVOLV, INC. (US) | 2022-08-23 | — | — | US | disclosed |