SCHEMBL29773756

SCHEMBL29773756

CC(C)CCCCCCCCCCC1CC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N2CCC[C@H]2C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N1

nearest known ligand 0.52

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ PLG P00747 1/20 0.51
▸ KRAS P01116 4/20 0.48
▸ FLT1 P17948 1/20 0.48
▸ HDAC4 P56524 2/20 0.47
▸ ELANE P08246 4/20 0.47
▸ HDAC3 O15379 1/20 0.47
▸ HDAC1 Q13547 1/20 0.47
▸ HDAC2 Q92769 1/20 0.47
▸ HDAC10 Q969S8 1/20 0.47
▸ HDAC11 Q96DB2 1/20 0.47
▸ HDAC6 Q9UBN7 1/20 0.47
▸ NTSR1 P30989 4/20 0.46
▸ KLKB1 P03952 1/20 0.45
▸ TFPI P10646 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29884109 0.97 KRAS (0.49) PLGKRASFLT1HDAC4ELANE
SCHEMBL29773704 0.97 KRAS (0.49) PLGKRASFLT1HDAC4ELANE
SCHEMBL29773696 0.97 KRAS (0.49) PLGKRASFLT1HDAC4ELANE
SCHEMBL29390495 0.97 KRAS (0.49) PLGKRASFLT1HDAC4ELANE
SCHEMBL12131181 0.96 ELANE (0.51) PLGKRASFLT1ELANETFPI
SCHEMBL29773738 0.94 PLG (0.52) PLGKRASFLT1HDAC4ELANE
SCHEMBL29390178 0.93 PLG (0.51) PLGKRASFLT1HDAC4ELANE
Bacillomycin D(C14) SCHEMBL29777427 0.92 SLC6A3 (0.52) PLGKRASFLT1HDAC4ELANE
SCHEMBL29884584 0.92 KRAS (0.47) PLGKRASFLT1HDAC4ELANE
SCHEMBL30928172 0.92 PLG (0.49) PLGKRASHDAC4ELANEHDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250270567-A1 GENERATION OF ACYL AMINO ACIDS MODULAR GENETICS INC (US) 2025-08-28 — — US disclosed
US-12123004-B2 Generation of acyl amino acids MODULAR GENETICS, INC. (US) 2024-10-22 — — US disclosed
US-12031167-B2 Generation of acyl amino acids MODULAR GENETICS, INC. (US) 2024-07-09 — — US disclosed
US-20220259626-A1 GENERATION OF ACYL AMINO ACIDS MODULAR GENETICS, INC. 2022-08-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220259626-A1 GENERATION OF ACYL AMINO ACIDS FADS1, FADS2, FAR1 PLG 1385/4885KRAS 973/4885FLT1 1562/4885
US-12031167-B2 Generation of acyl amino acids FADS1, FADS2, FAR1 PLG 1385/4885KRAS 973/4885FLT1 1562/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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