Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL262337 | 0.87 | KDM4E (0.50) | KDM4EALDH1A1HSD17B10EPHX2L3MBTL1 | |
| Alpha-Terthienyl SCHEMBL147274 | 0.78 | DPP4 (0.65) | DPP4KDM4EALDH1A1HSD17B10LTA4H | |
| SCHEMBL499333 | 0.78 | DPP4 (0.65) | DPP4KDM4EALDH1A1HSD17B10LTA4H | |
| SCHEMBL15957843 | 0.78 | DPP4 (0.65) | DPP4KDM4EALDH1A1HSD17B10LTA4H | |
| SCHEMBL1105086 | 0.78 | DPP4 (0.65) | DPP4KDM4EALDH1A1HSD17B10LTA4H | |
| SCHEMBL23611278 | 0.78 | DPP4 (0.65) | DPP4KDM4EALDH1A1HSD17B10LTA4H | |
| SCHEMBL2742433 | 0.78 | DPP4 (0.65) | DPP4KDM4EALDH1A1HSD17B10LTA4H | |
| SCHEMBL14703073 | 0.78 | DPP4 (0.65) | DPP4KDM4EALDH1A1HSD17B10LTA4H | |
| SCHEMBL13707354 | 0.78 | DPP4 (0.65) | DPP4KDM4EALDH1A1HSD17B10LTA4H | |
| SCHEMBL13942801 | 0.78 | DPP4 (0.65) | DPP4KDM4EALDH1A1HSD17B10LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427447-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | Pike Pharma GmbH (CH) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128163-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | PIKE PHARMA GMBH (CH) | 2010-11-11 | — | — | WO | disclosed |