Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL298864 | 0.87 | DPP4 (0.46) | KDM4EALDH1A1HSD17B10EPHX2RAB9A | |
| SCHEMBL11991177 | 0.75 | KDM4E (0.73) | KDM4EALDH1A1HSD17B10EPHX2RAB9A | |
| SCHEMBL3068196 | 0.72 | FBP1 (0.48) | ALDH1A1HSD17B10HPGDCYP1A2 | |
| SCHEMBL16291133 | 0.69 | L3MBTL1 (0.57) | KDM4EALDH1A1HSD17B10EPHX2RAB9A | |
| SCHEMBL3545 | 0.69 | L3MBTL1 (0.57) | KDM4EALDH1A1HSD17B10EPHX2RAB9A | |
| SCHEMBL13977912 | 0.69 | KDM4E (0.52) | KDM4EALDH1A1HSD17B10EPHX2RAB9A | |
| SCHEMBL572719 | 0.68 | PDPK1 (0.45) | KDM4EALDH1A1RAB9AKMT2AHPGD | |
| SCHEMBL4648 | 0.68 | PDPK1 (0.56) | KDM4EALDH1A1HSD17B10EPHX2RAB9A | |
| SCHEMBL5012609 | 0.68 | NPC1 (0.41) | KDM4EALDH1A1HSD17B10RAB9AHPGD | |
| Hydrogen Sulfide SCHEMBL22588115 | 0.67 | L3MBTL1 (0.55) | KDM4EALDH1A1HSD17B10EPHX2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3352570-B1 | HETEROCYCLIC TRIFLUOROALKENYL COMPOUNDS HAVING A NEMATOCIDAL ACTIVITY, THEIR AGRONOMIC COMPOSITIONS AND USE THEREOF | ISAGRO SPA (IT) | 2020-04-08 | — | — | EP | claimed |
| US-20180271097-A1 | HETEROCYCLIC TRIFLUOROALKENYL COMPOUNDS HAVING A NEMATOCIDAL ACTIVITY, THEIR AGRONOMIC COMPOSITIONS AND USE THEREOF | ISAGRO S.P.A. (IT) | 2018-09-27 | — | — | US | claimed |
| CN-111995620-B | Preparation method of 1,3, 4-thiadiazole compound and compound prepared by same | 重庆医科大学 | 2023-06-06 | — | — | CN | disclosed |
| EP-3352570-B1 | HETEROCYCLIC TRIFLUOROALKENYL COMPOUNDS HAVING A NEMATOCIDAL ACTIVITY, THEIR AGRONOMIC COMPOSITIONS AND USE THEREOF | ISAGRO SPA (IT) | 2020-04-08 | — | — | EP | disclosed |
| US-20180271097-A1 | HETEROCYCLIC TRIFLUOROALKENYL COMPOUNDS HAVING A NEMATOCIDAL ACTIVITY, THEIR AGRONOMIC COMPOSITIONS AND USE THEREOF | ISAGRO S.P.A. (IT) | 2018-09-27 | — | — | US | disclosed |
| US-9758502-B2 | Dihydropyrone compounds and herbicides comprising the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-09-12 | — | — | US | disclosed |
| EP-2925736-B1 | DIHYDROPYRONE COMPOUNDS AND HERBICIDES COMPRISING THE SAME | SUMITOMO CHEMICAL CO (JP) | 2017-01-04 | — | — | EP | disclosed |
| US-20150299156-A1 | DIHYDROPYRONE COMPOUNDS AND HERBICIDES COMPRISING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-10-22 | — | — | US | disclosed |
| EP-2925736-A1 | DIHYDROPYRONE COMPOUNDS AND HERBICIDES COMPRISING THE SAME | Sumitomo Chemical Co., Ltd (JP) | 2015-10-07 | — | — | EP | disclosed |
| WO-2014084407-A1 | DIHYDROPYRONE COMPOUNDS AND HERBICIDES COMPRISING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-06-05 | — | — | WO | disclosed |
| EP-2222667-B1 | NOVEL THIOPHENE DERIVATIVES AS AGONISTS OF S1P1/EDG1 | ACTELION PHARMACEUTICALS LTD (CH) | 2013-02-20 | — | — | EP | disclosed |
| US-4093804-A | ANTIBIOTICS | YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) | 1978-06-06 | — | — | US | disclosed |
| US-4093802-A | ANTIBIOTICS | YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) | 1978-06-06 | — | — | US | disclosed |
| US-4045438-A | Cephalosporin antibiotics | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 1977-08-30 | — | — | US | disclosed |
| US-4044000-A | Substituted β-lactam antibiotics | ELI LILLY AND COMPANY (US) | 1977-08-23 | — | — | US | disclosed |
| US-4031083-A | Cephalosporin antibiotics | YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) | 1977-06-21 | — | — | US | disclosed |
| US-4026887-A | Cephalosporin antibiotics | YEDA RESEARCH & DEVELOPMENT CO. LTD. (IL) | 1977-05-31 | — | — | US | disclosed |
| US-3994875-A | CEPHALOSPORINS, PENICILLINS | YEDA RESEARCH & DEVELOPMENT CO. LTD. (IL) | 1976-11-30 | — | — | US | disclosed |
| US-3994885-A | WITH ALKALI METAL ALKOXIDE, HALOGENATION | ELI LILLY AND COMPANY (US) | 1976-11-30 | — | — | US | disclosed |
| US-3948904-A | ANTIBIOTICS | YEDA RESEARCH & DEVELOPMENT CO. LTD. (IL) | 1976-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180271097-A1 | HETEROCYCLIC TRIFLUOROALKENYL COMPOUNDS HAVING A NEMATOCIDAL ACTIVITY, THEIR AGRONOMIC COMPOSITIONS AND USE THEREOF | CYP8B1, CYCS, LSS | KDM4E 2509/4885ALDH1A1 3826/4885HSD17B10 593/4885 |
| US-20150299156-A1 | DIHYDROPYRONE COMPOUNDS AND HERBICIDES COMPRISING THE SAME | CBR3, DDT, WEE2 | KDM4E 699/4885ALDH1A1 463/4885HSD17B10 147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.