Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 15/20 | 0.57 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.54 |
| ▸ | PRKDC | P78527 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29886145 | 1.00 | ATR (0.57) | ATRADORA2AADORA1PRKDCMAPK1 | |
| SCHEMBL32688927 | 0.91 | ATR (0.66) | ATRPRKDC | |
| SCHEMBL6701248 | 0.91 | ATR (0.66) | ATRPRKDC | |
| SCHEMBL29886664 | 0.85 | ATR (0.71) | ATR | |
| SCHEMBL13137948 | 0.83 | ATR (0.87) | ATR | |
| SCHEMBL6701889 | 0.82 | ADORA1 (0.56) | ATRADORA2AADORA1PRKDC | |
| SCHEMBL12198431 | 0.82 | ATR (0.56) | ATRADORA2AADORA1PRKDC | |
| SCHEMBL934795 | 0.82 | ADORA1 (0.56) | ATRADORA2AADORA1PRKDC | |
| SCHEMBL6696565 | 0.78 | ATR (0.57) | ATRADORA2AADORA1PRKDC | |
| SCHEMBL6697532 | 0.78 | ATR (0.57) | ATRADORA2AADORA1PRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260077068-A1 | ATP-INDEPENDENT BIOLUMINESCENT REPORTER VARIANTS TO IMPROVE IN VIVO IMAGING | UNIV VIRGINIA PATENT FOUNDATION (US) | 2026-03-19 | — | — | US | disclosed |
| US-20220259574-A1 | ATP-INDEPENDENT BIOLUMINESCENT REPORTER VARIANTS TO IMPROVE IN VIVO IMAGING | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2022-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260077068-A1 | ATP-INDEPENDENT BIOLUMINESCENT REPORTER VARIANTS TO IMPROVE IN VIVO IMAGING | KCNN2, KCNN1, ATP1B2 | ATR 2600/4885ADORA2A 725/4885ADORA1 629/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.