SCHEMBL29889197

SCHEMBL29889197

N=C(N)NCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](N)CC(=O)O)C(=O)N[C@@H](CC(=O)O)C(N)=O

nearest known ligand 0.49

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 15/20 0.49
▸ NPY1R P25929 9/20 0.49
▸ NPY5R Q15761 8/20 0.49
▸ NPY2R P49146 5/20 0.49
▸ KEAP1 Q14145 1/20 0.42
▸ CTSL P07711 1/20 0.42
▸ KISS1R Q969F8 1/20 0.41
▸ MC4R P32245 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30475880 0.97 NPY4R (0.49) NPY4RNPY1RNPY5RNPY2RCTSL
SCHEMBL29634991 0.96 NPY4R (0.50) NPY4RNPY1RNPY5RNPY2RCTSL
SCHEMBL29889146 0.95 NPY4R (0.46) NPY4RNPY1RNPY5RNPY2R
SCHEMBL30475873 0.94 NPY4R (0.45) NPY4RNPY1RNPY5RNPY2R
SCHEMBL29482469 0.94 NPY4R (0.45) NPY4RNPY1RNPY5RNPY2R
SCHEMBL30475882 0.93 NPY4R (0.49) NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL30475874 0.93 NPY4R (0.49) NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL22117541 0.92 NPY4R (0.54) NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL22117539 0.92 NPY4R (0.54) NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL30948383 0.91 NPY4R (0.45) NPY4RNPY1RNPY5RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230212549-A1 COMPOUNDS COMPRISING A FIBROBLAST ACTIVATION PROTEIN LIGAND AND USE THEREOF 3B PHARMACEUTICALS GMBH (DE) 2023-07-06 — — US disclosed
US-20220315554-A1 COMPOUNDS COMPRISING A FIBROBLAST ACTIVATION PROTEIN LIGAND AND USE THEREOF 3B PHARMACEUTICALS GMBH (DE) 2022-10-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220315554-A1 COMPOUNDS COMPRISING A FIBROBLAST ACTIVATION PROTEIN LIGAND AND USE THEREOF FIBP, FN1, TPX2 NPY4R 199/4885NPY1R 160/4885NPY5R 227/4885
US-20230212549-A1 COMPOUNDS COMPRISING A FIBROBLAST ACTIVATION PROTEIN LIGAND AND USE THEREOF FIBP, FN1, TPX2 NPY4R 199/4885NPY1R 160/4885NPY5R 227/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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