Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 13/20 | 0.62 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.54 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.54 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.54 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | DCAF1 | Q9Y4B6 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30599066 | 0.80 | MAPK1 (0.63) | MAPK1MAPK3TAOK1PRKD2CNR2 | |
| SCHEMBL23222036 | 0.80 | MAPK1 (0.63) | MAPK1MAPK3TAOK1PRKD2CNR2 | |
| SCHEMBL31167636 | 0.78 | MAPK1 (0.61) | MAPK1MAPK3TAOK1PRKD2CNR2 | |
| SCHEMBL31167639 | 0.78 | MAPK1 (0.61) | MAPK1MAPK3TAOK1PRKD2CNR2 | |
| SCHEMBL23203339 | 0.74 | CDK9 (0.53) | CCNT1 | |
| SCHEMBL21588045 | 0.74 | MAPK1 (0.65) | MAPK1MAPK3TAOK1PRKD2DCAF1 | |
| SCHEMBL23203318 | 0.74 | MAPK1 (0.65) | MAPK1MAPK3TAOK1PRKD2DCAF1 | |
| SCHEMBL14338329 | 0.73 | MAPK1 (0.76) | MAPK1MAPK3TAOK1PRKD2RPS6KB1 | |
| SCHEMBL5385189 | 0.73 | MAPK1 (0.76) | MAPK1MAPK3TAOK1PRKD2RPS6KB1 | |
| SCHEMBL21587724 | 0.72 | MAPK1 (0.62) | MAPK1MAPK3TAOK1PRKD2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4048270-A1 | PHARMACEUTICAL COMBINATION OF PRMT5 INHIBITORS | Lupin Limited (IN) | 2022-08-31 | — | — | EP | disclosed |