Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TMPRSS4 | Q9NRS4 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3324051 | 1.00 | NOTUM (0.44) | NOTUML3MBTL1CYP3A4TSHRMAPK1 | |
| SCHEMBL1410268 | 0.82 | TMPRSS4 (0.51) | NOTUML3MBTL1CYP3A4TSHRMAPK1 | |
| SCHEMBL31193921 | 0.82 | TMPRSS4 (0.51) | NOTUML3MBTL1CYP3A4TSHRMAPK1 | |
| SCHEMBL11550638 | 0.79 | TSHR (0.60) | L3MBTL1CYP3A4TSHRMAPK1TDP1 | |
| SCHEMBL3789153 | 0.78 | CYP3A4 (0.52) | CYP3A4TSHRMAPK1TDP1TMPRSS4 | |
| SCHEMBL12251280 | 0.77 | TSHR (0.41) | CYP3A4TSHRMAPK1TDP1CYP1A2 | |
| SCHEMBL672252 | 0.76 | NOTUM (0.47) | NOTUML3MBTL1TSHRMAPK1TDP1 | |
| SCHEMBL29403188 | 0.76 | TSHR (0.62) | NOTUMCYP3A4TSHRMAPK1TDP1 | |
| SCHEMBL107751 | 0.76 | TSHR (0.62) | NOTUMCYP3A4TSHRMAPK1TDP1 | |
| SCHEMBL5865588 | 0.75 | CYP3A4 (0.53) | NOTUML3MBTL1CYP3A4TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4185592-A1 | INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF | Annexon, Inc. (US) | 2023-05-31 | — | — | EP | disclosed |
| CN-110248940-B | Aryl hydrocarbon receptor (AhR) modulator compounds | 菲尼克斯药品股份公司 | 2022-07-01 | — | — | CN | disclosed |