Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 2/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.39 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29403188 | 1.00 | TSHR (0.62) | TSHRCYP3A4MAPK1TDP1TP53 | |
| SCHEMBL5423724 | 0.91 | TSHR (0.54) | TSHRCYP3A4MAPK1TDP1TP53 | |
| SCHEMBL21995301 | 0.83 | TSHR (0.60) | TSHRCYP3A4MAPK1TDP1TP53 | |
| SCHEMBL3789153 | 0.82 | CYP3A4 (0.52) | TSHRCYP3A4MAPK1TDP1TP53 | |
| SCHEMBL16211981 | 0.81 | TSHR (0.58) | TSHRCYP3A4MAPK1TDP1TP53 | |
| SCHEMBL31740316 | 0.81 | TSHR (0.58) | TSHRCYP3A4MAPK1TDP1TP53 | |
| SCHEMBL29649700 | 0.80 | IDO1 (0.50) | TSHRCYP3A4MAPK1TDP1TP53 | |
| SCHEMBL987352 | 0.80 | IDO1 (0.50) | TSHRCYP3A4MAPK1TDP1TP53 | |
| SCHEMBL3789260 | 0.78 | PDE2A (0.56) | TSHRKMOTMPRSS4DAO | |
| SCHEMBL30898355 | 0.78 | KIF11 (0.48) | TSHRCYP3A4MAPK1TDP1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 350 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117913360-A | Battery electrolyte and application thereof | 香河昆仑新能源材料股份有限公司 | 2024-04-19 | — | — | CN | claimed |
| CN-117800808-A | Preparation method of 2, 4-dichloro fluorobenzene | 帕潘纳(北京)科技有限公司 | 2024-04-02 | — | — | CN | claimed |
| CN-114539194-B | Synthesis method of 2,2' -di (trifluoromethyl) -4,4', 5' -biphenyl dianhydride | 常州市阳光药业有限公司 | 2024-03-29 | — | — | CN | claimed |
| CN-117747947-A | Non-aqueous electrolyte of lithium ion battery and lithium ion battery | 香河昆仑新能源材料股份有限公司 | 2024-03-22 | — | — | CN | claimed |
| CN-117747945-A | Electrolyte containing siloxane compound and energy storage device containing electrolyte | 香河昆仑新能源材料股份有限公司 | 2024-03-22 | — | — | CN | claimed |
| CN-117728029-A | Electrolyte containing silasulfane compound and energy storage device containing electrolyte | 香河昆仑新能源材料股份有限公司 | 2024-03-19 | — | — | CN | claimed |
| CN-114105726-B | Preparation method of 2, 4-dichloro benzotrifluoride | 江苏三美化工有限公司 | 2024-01-19 | — | — | CN | claimed |
| CN-117175010-A | Electrolyte additive containing phosphorus and boron elements, electrolyte and application thereof | 香河昆仑新能源材料股份有限公司 | 2023-12-05 | — | — | CN | claimed |
| CN-117133982-A | Nonaqueous electrolyte and secondary battery | 香河昆仑新能源材料股份有限公司 | 2023-11-28 | — | — | CN | claimed |
| CN-117133981-A | Nonaqueous electrolyte and secondary battery | 香河昆仑新能源材料股份有限公司 | 2023-11-28 | — | — | CN | claimed |
| US-7598413-B2 | Process for producing fluorine-containing alkylsulfonylaminoethyl α-substituted acrylate | CENTRAL GLASS COMPANY, LIMITED (JP) | 2009-10-06 | — | — | US | claimed |
| US-20090069595-A1 | Process for Producing Fluorine-Containing Alkylsulfonylaminoethyl Alpha-Substituted Acrylate | CENTRAL GLASS COMPANY, LIMITED (JP) | 2009-03-12 | — | — | US | claimed |
| EP-1502908-B1 | Process for fluorurating ethers | MITENI SPA (IT) | 2007-09-12 | — | — | EP | claimed |
| EP-1502908-A1 | Process for fluorurating ethers | MITENI S.p.A. (IT) | 2005-02-02 | — | — | EP | claimed |
| US-20020022748-A1 | Process for purifying 1,1,1,5,5,5-hexafluoroacetylacetone | CENTRAL GLASS COMPANY, LIMITED (JP) | 2002-02-21 | — | — | US | claimed |
| EP-0872468-B1 | Method for producing 3,3-dichloro-1,1,1-trifluoroacetone | CENTRAL GLASS CO LTD (JP) | 2001-07-25 | — | — | EP | claimed |
| US-5976702-A | ORGANOSILICON COMPOUNDS | ASAHI GLASS COMPANY LTD. (JP) | 1999-11-02 | — | — | US | claimed |
| US-5905174-A | FLUORINATING PENTACHLOROACETONE WITH HYDROGEN FLUORIDE IN THE PRESENCE OF A CATALYST | CENTRAL GLASS COMPANY, LIMITED (JP) | 1999-05-18 | — | — | US | claimed |
| EP-0872468-A1 | Method for producing 3,3-dichloro-1,1,1-trifluoroacetone | Central Glass Company, Limited (JP) | 1998-10-21 | — | — | EP | claimed |
| EP-0137424-A2 | Process for producing 2,4-dichlorobenzotrifluoride | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1985-04-17 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020022748-A1 | Process for purifying 1,1,1,5,5,5-hexafluoroacetylacetone | HDHD5, HK1, ADH1C | TSHR 4325/4885CYP3A4 2637/4885MAPK1 544/4885 |
| US-20090069595-A1 | Process for Producing Fluorine-Containing Alkylsulfonylaminoethyl Alpha-Substituted Acrylate | AFF1, AFF2, AFF4 | TSHR 157/4885CYP3A4 2065/4885MAPK1 612/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.