SCHEMBL29890735

SCHEMBL29890735

COC(=O)/C(=C\O)Oc1cc(C2CCCC2)ccc1C

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PDE4B Q07343 12/20 0.39
PDE4A P27815 4/20 0.39
PDE4C Q08493 4/20 0.39
PDE4D Q08499 4/20 0.39
ACMSD Q8TDX5 2/20 0.36
QDPR P09417 1/20 0.36
HDAC1 Q13547 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29106882 1.00 PDE4B (0.39) PDE4BPDE4APDE4CPDE4DACMSD
SCHEMBL30598396 1.00 PDE4B (0.39) PDE4BPDE4APDE4CPDE4DACMSD
SCHEMBL29891091 0.99 PDE4B (0.38) PDE4BPDE4APDE4CPDE4DACMSD
SCHEMBL27082810 0.99 PDE4B (0.38) PDE4BPDE4APDE4CPDE4DACMSD
SCHEMBL29913621 0.89 PDE4B (0.38) PDE4BPDE4APDE4CPDE4DACMSD
SCHEMBL22488380 0.89 PDE4B (0.38) PDE4BPDE4APDE4CPDE4DACMSD
SCHEMBL23795758 0.88 PDE4B (0.37) PDE4BPDE4APDE4CPDE4DACMSD
SCHEMBL29913636 0.88 PDE4B (0.37) PDE4BPDE4APDE4CPDE4DACMSD
SCHEMBL30293904 0.88 PDE4B (0.37) PDE4BPDE4APDE4CPDE4DACMSD
SCHEMBL29767026 0.88 PDE4B (0.37) PDE4BPDE4APDE4CPDE4DACMSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240190806-A1 CHEMICAL PROCESS SYNGENTA CROP PROTECTION AG (CH) 2024-06-13 US disclosed
EP-4313925-A1 CHEMICAL PROCESS Syngenta Crop Protection AG (CH) 2024-02-07 EP disclosed
WO-2022200579-A1 CHEMICAL PROCESS SYNGENTA CROP PROTECTION AG (CH) 2022-09-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240190806-A1 CHEMICAL PROCESS CYP1B1, CYP1A1, DHPS PDE4B 1217/4885PDE4A 1733/4885PDE4C 1526/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.