Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | GLP1R | P43220 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20470650 | 1.00 | SMN1; SMN2 (0.31) | SMN1; SMN2MAPTGLP1RADORA3 | |
| SCHEMBL3508026 | 0.70 | NMT1 (0.33) | SMN1; SMN2MAPT | |
| SCHEMBL29890839 | 0.69 | KIF11 (0.37) | SMN1; SMN2 | |
| SCHEMBL20470651 | 0.69 | KIF11 (0.37) | SMN1; SMN2 | |
| SCHEMBL617623 | 0.65 | — | — | |
| SCHEMBL29393836 | 0.64 | — | — | |
| SCHEMBL17573283 | 0.64 | SMN1; SMN2 (0.33) | SMN1; SMN2MAPT | |
| SCHEMBL26381008 | 0.64 | — | — | |
| SCHEMBL5561814 | 0.64 | SMN1; SMN2 (0.46) | SMN1; SMN2MAPT | |
| SCHEMBL21243790 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4200015-A1 | SUBSTITUTED HETEROARYL COMPOUNDS USEFUL AS INHIBITORS OF TLR9 | Bristol-Myers Squibb Company (US) | 2023-06-28 | — | — | EP | disclosed |
| CN-115956077-A | Substituted heteroaryl compounds as TLR9 inhibitors | 百时美施贵宝公司 | 2023-04-11 | — | — | CN | disclosed |
| CN-110248940-B | Aryl hydrocarbon receptor (AhR) modulator compounds | 菲尼克斯药品股份公司 | 2022-07-01 | — | — | CN | disclosed |