Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | GPR3 | P46089 | 3/20 | 0.39 |
| ▸ | FABP7 | O15540 | 1/20 | 0.38 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.38 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1477053 | 1.00 | GRM5 (0.48) | GRM5FFAR1PTPN1SLC22A12GPR3 | |
| SCHEMBL99250 | 0.81 | FFAR1 (0.50) | GRM5FFAR1SLC22A12GPR3NOTUM | |
| SCHEMBL29478762 | 0.81 | GRM5 (0.48) | GRM5FFAR1CETPKAT6A | |
| SCHEMBL1855558 | 0.81 | GRM5 (0.48) | GRM5FFAR1SLC22A12GPR3KIF11 | |
| SCHEMBL689277 | 0.81 | GRM5 (0.48) | GRM5FFAR1CETPKAT6A | |
| SCHEMBL4293314 | 0.81 | GRM5 (0.48) | GRM5FFAR1SLC22A12GPR3KIF11 | |
| SCHEMBL14805731 | 0.81 | FABP7 (0.38) | GRM5FFAR1PTPN1FABP7FABP5 | |
| SCHEMBL3147185 | 0.79 | GPR3 (0.50) | SLC22A12GPR3KIF11CETPCHRM2 | |
| SCHEMBL16984726 | 0.78 | GRM5 (0.56) | GRM5FFAR1GPR3HAO1KIF11 | |
| SCHEMBL81119 | 0.78 | FFAR1 (0.54) | GRM5FFAR1NOTUMHAO1KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118103038-A | 17 Beta-hydroxysteroid dehydrogenase 13 inhibitors and methods of use thereof | 英安塔制药有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-110248940-B | Aryl hydrocarbon receptor (AhR) modulator compounds | 菲尼克斯药品股份公司 | 2022-07-01 | — | — | CN | disclosed |