Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 19/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24429937 | 1.00 | WDR5 (0.80) | WDR5KMT2AALDH1A1CYP2D6GAA | |
| SCHEMBL24429939 | 0.90 | WDR5 (0.80) | WDR5KMT2AALDH1A1CYP2D6GAA | |
| SCHEMBL29890970 | 0.90 | WDR5 (0.80) | WDR5KMT2AALDH1A1CYP2D6GAA | |
| SCHEMBL29544609 | 0.89 | WDR5 (1.00) | WDR5KMT2A | |
| SCHEMBL24429879 | 0.89 | WDR5 (1.00) | WDR5KMT2A | |
| SCHEMBL24429921 | 0.87 | WDR5 (0.76) | WDR5KMT2AALDH1A1CYP2D6GAA | |
| SCHEMBL29891312 | 0.87 | WDR5 (0.79) | WDR5KMT2AALDH1A1CYP2D6GAA | |
| SCHEMBL24429882 | 0.87 | WDR5 (0.79) | WDR5KMT2AALDH1A1CYP2D6GAA | |
| SCHEMBL29891004 | 0.87 | WDR5 (0.76) | WDR5KMT2AALDH1A1CYP2D6GAA | |
| SCHEMBL24429900 | 0.86 | WDR5 (0.75) | WDR5KMT2AALDH1A1CYP2D6GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109734674-B | Aniline WDR5 protein-protein interaction inhibitor and preparation method and application thereof | 中国药科大学 | 2022-08-26 | — | — | CN | disclosed |