Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ5 | P48544 | 1/20 | 0.43 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.43 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.43 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PKLR | P30613 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | BCL6 | P41182 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5536990 | 1.00 | KCNJ5 (0.43) | KCNJ5KCNJ3KCNQ1CACNA1CPIK3CD | |
| SCHEMBL23410154 | 0.89 | KCNJ5 (0.48) | KCNJ5KCNJ3KCNQ1CACNA1CPIK3CD | |
| SCHEMBL29892541 | 0.89 | KCNJ5 (0.48) | KCNJ5KCNJ3KCNQ1CACNA1CPIK3CD | |
| SCHEMBL29891682 | 0.85 | MCHR1 (0.46) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL5527743 | 0.85 | MCHR1 (0.46) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL5534501 | 0.84 | MAOA (0.47) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL29892563 | 0.84 | MAOA (0.47) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL23410148 | 0.83 | WEE1 (0.39) | KDM4EALDH1A1MEN1KMT2AMAOA | |
| SCHEMBL23410121 | 0.83 | MAPK1 (0.39) | KDM4EALDH1A1MEN1KMT2AMAOA | |
| SCHEMBL23411784 | 0.83 | KDM4E (0.44) | KCNJ5KCNJ3KCNQ1CACNA1CPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119564686-A | DGK alpha inhibitors as immune activation substituted aminoquinolones of (2) | 拜耳公司 | 2025-03-07 | — | — | CN | disclosed |
| CN-119523983-A | DGK alpha inhibitors as immune activation substituted aminoquinolones of (2) | 拜耳公司 | 2025-02-28 | — | — | CN | disclosed |
| CN-119424429-A | DGK alpha inhibitors as immune activation substituted aminoquinolones of (2) | 拜耳公司 | 2025-02-14 | — | — | CN | disclosed |
| CN-115003665-B | DGK alpha inhibitors as immune activation substituted aminoquinolones of (2) | 拜耳公司 | 2024-11-08 | — | — | CN | disclosed |
| CN-115003665-A | Substituted aminoquinolones as immunoactive DGK alpha inhibitors | 拜耳公司 | 2022-09-02 | — | — | CN | disclosed |