SCHEMBL29891719

SCHEMBL29891719

C#Cc1ccc(F)cc1C(F)(F)F

nearest known ligand 0.43

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
AR P10275 16/20 0.43
IDO1 P14902 2/20 0.42
PGR P06401 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3432674 1.00 AR (0.43) ARIDO1PGR
SCHEMBL20455559 0.83 IDO1 (0.38) ARIDO1
SCHEMBL29892139 0.83 IDO1 (0.38) ARIDO1
SCHEMBL26359609 0.82 PTGS1 (0.36) IDO1
SCHEMBL6211022 0.79 AR (0.43) ARIDO1PGR
SCHEMBL9793597 0.79 AR (0.39) AR
SCHEMBL221383 0.79 AR (0.62) ARPGR
SCHEMBL17672739 0.78 AR (0.50) ARPGR
SCHEMBL1762580 0.78 GAA (0.55) AR
SCHEMBL31019374 0.78 GAA (0.55) AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112119076-B Spiropiperidine allosteric modulators of nicotinic acetylcholine receptors 默沙东有限责任公司 2025-01-10 CN disclosed
CN-110248940-B Aryl hydrocarbon receptor (AhR) modulator compounds 菲尼克斯药品股份公司 2022-07-01 CN disclosed