Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.41 |
| ▸ | KDM6B | O15054 | 3/20 | 0.41 |
| ▸ | KDM4D | Q6B0I6 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | LATS1 | O95835 | 4/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.39 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ATR | Q13535 | 1/20 | 0.37 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4075291 | 0.86 | NAMPT (0.42) | NAMPTCYP3A4CYP17A1RAB9ALATS1 | |
| SCHEMBL30759275 | 0.85 | NAMPT (0.43) | NAMPTCYP3A4CYP17A1RAB9ALATS1 | |
| SCHEMBL38663420 | 0.84 | HDAC3 (0.46) | NAMPTCYP3A4CYP17A1LATS1TGFBR1 | |
| SCHEMBL27077511 | 0.80 | KDM4C (0.51) | KDM4CKDM6BKDM4DEGLN3IRAK4 | |
| SCHEMBL5551442 | 0.77 | SIRT3 (0.47) | NAMPTIRAK4CYP17A1RAB9ATGFBR1 | |
| SCHEMBL12968584 | 0.77 | AURKB (0.39) | NAMPTCYP3A4 | |
| SCHEMBL18421265 | 0.76 | KDM4C (0.51) | KDM4CKDM6BKDM4DEGLN3IRAK4 | |
| SCHEMBL535637 | 0.75 | KDM4C (0.58) | NAMPTKDM4CKDM6BKDM4DEGLN3 | |
| SCHEMBL18421178 | 0.74 | TSHR (0.49) | KDM4CKDM6BKDM4DEGLN3IRAK4 | |
| SCHEMBL29892972 | 0.74 | KDM4C (0.52) | KDM4CKDM6BKDM4DEGLN3IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4313308-A1 | TEAD INHIBITORS AND USES THEREOF | Cedilla Therapeutics, Inc. (US) | 2024-02-07 | — | — | EP | disclosed |
| US-20230098872-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. | 2023-03-30 | — | — | US | disclosed |
| WO-2022204452-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2022-09-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230098872-A1 | TEAD INHIBITORS AND USES THEREOF | TEAD2, TEAD3, TEAD4 | NAMPT 78/4885KDM4C 3045/4885KDM6B 1372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.