TEAD3 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL4792952	0.63	4/20
SCHEMBL4792411	0.66	3/20
SCHEMBL2788730	0.53	3/20
SCHEMBL3891265	0.60	2/20
SCHEMBL7246438	0.60	2/20
SCHEMBL7395255	0.59	2/20
SCHEMBL6855553	0.58	2/20
SCHEMBL6942319	0.56	2/20
SCHEMBL6944656	0.56	2/20
SCHEMBL8099349	0.56	2/20
SCHEMBL5029372	0.56	2/20
SCHEMBL6944485	0.55	2/20
SCHEMBL8108121	0.55	2/20
SCHEMBL489015	0.54	2/20
SCHEMBL7387110	0.54	2/20
SCHEMBL6941703	0.54	2/20
SCHEMBL6941768	0.54	2/20
SCHEMBL8108207	0.54	2/20
SCHEMBL8109617	0.54	2/20
SCHEMBL3884461	0.54	2/20

Clinical trials — most relevant to TEAD3 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Compared the Efficacy and Safety of CDOP Combined With Chidamide and CDOP in de Novo Peripheral T Cell Lymphoma Patients	PHASE3	UNKNOWN
PhII 5-Azacytidine Plus Valproic Acid and Eventually Atra in Intermediate II and High Risk MDS	PHASE2	COMPLETED
Neoadjuvant Zoledronate and Atorvastatin in Triple Negative Breast Cancer	PHASE2	COMPLETED
SCARFREE-001: Verteporfin for Scar Prevention	PHASE2	NOT_YET_RECRUITING
Study of the Beach Regimen on Relapsed/Refractory Acute Myeloid Leukemia (R/R AML)	PHASE2	ACTIVE_NOT_RECRUITING
An Open-Label, Proof of Consent Study of Vorinostat for the Treatment of Mdoerate-to-Severe Crohn s Disease and Maintenance Therapy With Ustekinumab	PHASE1/PHASE2	RECRUITING
A Window of Opportunity Study of Pre-operative Endocrine Therapy With and Without Prometrium in Postmenopausal Women With Early Stage Breast Hormone Receptor Positive (HR+) Human Epidermal Receptor 2 Negative (HER2-) Breast Cancer.	PHASE2	UNKNOWN
Evaluation of the Safety and the Tolerability of a Combination of Two HIV Inducers in Patients With Undetectable Viral Load	PHASE1	COMPLETED
Epithelioid Haemangioendothelioma Observational Study	nan	RECRUITING
Patient's Derived Organoids for Drug Screening in Glioblastoma	nan	NOT_YET_RECRUITING
PHF19 Gene Expression and EZH2 Gene Deletion in Acute Myeloid Leukemia	nan	UNKNOWN
Green Tea Anticancer Mechanisms in Smokers	nan	COMPLETED
Autophagy in Systemic Lupus Erythematosus	nan	UNKNOWN
EGCG Modulate the Cytotoxic Effects of Chemotherapeutic Agents in Human Urothelial Carcinoma Cells	nan	UNKNOWN
Long Non-coding RNAs and Their Role on Epigenome as Diagnostic Markers in Childhood Acute Lymphoblastic Leukemia of T Cells.	nan	UNKNOWN
Endolymphatic Sac Tumors in a Population of Patients With Von Hippel-Lindau Disease:The Natural History and Pathobiology, and a Prospective Non-Randomized Clinical Trial of Hearing Preservation Surgery in Patients With Early Stage Endolymphatic Sac Tumors	nan	COMPLETED
Evaluation of the Predictive Effect of Inflammatory Markers in MI Patients	nan	UNKNOWN
Epigenomic Profiling of Circulating Cell-Free DNA (cfDNA) to Characterize the Dynamic Evolution of Molecular Subtypes in Extensive-Stage Small Cell Lung Cancer During First-Line Chemoimmunotherapy	nan	NOT_YET_RECRUITING
Gene Expression Variation and Implant Wound Healing Among Smokers and Diabetics	nan	COMPLETED
EPIgenetics and in Vivo Resistance of Chronic Myeloid Leukemia Stem Cells to Tyrosine Kinase Inhibitors	nan	UNKNOWN
Comparison Of Efficacy Of Tazarotene 0.045% Vs Halobetasol Propionate 0.01% Lotion For Treatment of Scalp Psoriasis	nan	COMPLETED
Diagnosis of RSTS: Identification of the Acetylation Profiles as Epigenetic Markers for Assessing Causality of CREBBP and EP300 Variants.	nan	UNKNOWN
Family Resilience Initiative Research Program	nan	UNKNOWN
EKLF Gene Expression in β-thalassemia	nan	NOT_YET_RECRUITING
Investigation of the Genetic and Environmental Causes of Autism: a Multi-Center Study	nan	NOT_YET_RECRUITING
Amplification of Zinc Finger Protein 217 Gene in Multiple Myeloma	nan	UNKNOWN
Tecfidera Diffusion Tensor Imaging	nan	COMPLETED
Sorting and Expression Profiling of Airway Cells From Humans (The SEARCH Study)	nan	COMPLETED
Mitochondrial Function of Immune Cells in Sepsis	nan	COMPLETED
Effect of Adenovirus E1A Oncogene on DNA Replication Dynamics	nan	UNKNOWN

Related proteins — ESM-2 sequence neighbours (a TEAD3 binder may also engage these)

Protein	Name	Similarity
Q90701	—	1.000	Q90701 →
P70210	—	1.000	P70210 →
P48984	—	1.000	P48984 →
TEAD4	Transcriptional enhancer factor TEF-3	1.000	landscape →
TEAD1	Transcriptional enhancer factor TEF-1	1.000	landscape →
Q62296	—	1.000	Q62296 →
Q19849	—	0.997	Q19849 →
P30051	—	0.996	P30051 →
TEAD2	Transcriptional enhancer factor TEF-4	0.995	landscape →
P30052	—	0.993	P30052 →
Q9JJP2	—	0.990	Q9JJP2 →
P48301	—	0.990	P48301 →
Q8TE85	—	0.989	Q8TE85 →
Q62141	—	0.988	Q62141 →
Q5FWH3	—	0.988	Q5FWH3 →
KAT2A	Histone acetyltransferase KAT2A	0.988	landscape →
Q6GL65	—	0.987	Q6GL65 →
Q07DV1	—	0.987	Q07DV1 →
Q66IH2	—	0.987	Q66IH2 →
Q3UQU0	—	0.987	Q3UQU0 →
Q8C0M0	—	0.987	Q8C0M0 →
Q9XSW2	—	0.986	Q9XSW2 →
B9EJA2	—	0.986	B9EJA2 →
Q8BHR2	—	0.986	Q8BHR2 →
O88480	—	0.986	O88480 →
Q04666	—	0.986	Q04666 →
Q2IBD4	—	0.986	Q2IBD4 →
Q5PQK8	—	0.986	Q5PQK8 →
F4HPA7	—	0.986	F4HPA7 →
P35428	—	0.986	P35428 →