Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5715880 | 1.00 | ALDH1A1 (0.59) | ALDH1A1GAAHTTMAPTKDM4E | |
| SCHEMBL5716060 | 0.98 | ALDH1A1 (0.56) | ALDH1A1GAAHTTMAPTKDM4E | |
| Hydrochloric Acid SCHEMBL15018127 | 0.96 | ALDH1A1 (0.59) | ALDH1A1GAAHTTMAPTKDM4E | |
| Hydrochloric Acid SCHEMBL29503396 | 0.96 | ALDH1A1 (0.59) | ALDH1A1GAAHTTMAPTKDM4E | |
| Hydrochloric Acid SCHEMBL28184619 | 0.94 | ALDH1A1 (0.58) | ALDH1A1GAAHTTMAPTKDM4E | |
| SCHEMBL6441668 | 0.83 | ALDH1A1 (0.65) | ALDH1A1GAAHTTMAPTKDM4E | |
| SCHEMBL29891888 | 0.83 | ALDH1A1 (0.65) | ALDH1A1GAAHTTMAPTKDM4E | |
| SCHEMBL5715714 | 0.81 | ALDH1A1 (0.61) | ALDH1A1GAAHTTMAPTKDM4E | |
| SCHEMBL25183852 | 0.80 | ALDH1A1 (0.59) | ALDH1A1GAAHTTMAPTKDM4E | |
| SCHEMBL3085534 | 0.80 | ALDH1A1 (0.71) | ALDH1A1GAAHTTMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4313295-A1 | PHARMACEUTICAL COMPOUNDS AS INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 19 (USP19) | Almac Discovery Limited (GB) | 2024-02-07 | — | — | EP | disclosed |
| WO-2022200523-A1 | PHARMACEUTICALS COMPOUNDS AS INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 19 (USP19) | ALMAC DISCOVERY LIMITED (GB) | 2022-09-29 | — | — | WO | disclosed |