Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 11/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | GALR3 | O60755 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | PRKACA | P17612 | 1/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.37 |
| ▸ | PRKACG | P22612 | 1/20 | 0.37 |
| ▸ | PRKACB | P22694 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15714749 | 0.71 | PARP1 (0.53) | PARP1CYP1A2KDM4EGAAALDH1A1 | |
| SCHEMBL22045317 | 0.71 | CDC25B (0.54) | PARP1CYP1A2KDM4EGAALCK | |
| SCHEMBL26826893 | 0.69 | CDC25B (0.72) | PARP1CYP1A2KDM4EGAAALDH1A1 | |
| SCHEMBL16695803 | 0.69 | PARP1 (0.54) | PARP1CYP1A2KDM4EALDH1A1HPGD | |
| SCHEMBL14647134 | 0.69 | PARP1 (0.50) | PARP1CYP1A2 | |
| SCHEMBL22045220 | 0.66 | LCK (0.55) | PARP1CYP1A2KDM4EGAAALDH1A1 | |
| SCHEMBL23870026 | 0.66 | PARP1 (0.53) | PARP1KDM4EGAAALDH1A1HPGD | |
| SCHEMBL31515754 | 0.66 | PARP1 (0.47) | PARP1CYP1A2HPGDLCKPRKACA | |
| SCHEMBL29792766 | 0.65 | PARP1 (1.00) | PARP1CYP1A2 | |
| SCHEMBL16695791 | 0.65 | PARP1 (1.00) | PARP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4313308-A1 | TEAD INHIBITORS AND USES THEREOF | Cedilla Therapeutics, Inc. (US) | 2024-02-07 | — | — | EP | disclosed |
| WO-2022204452-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2022-09-29 | — | — | WO | disclosed |