Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CCR4 | P51679 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ATR | Q13535 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2401876 | 1.00 | GAA (0.39) | GAAALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL19124135 | 0.85 | ALDH1A1 (0.40) | GAAALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL14449904 | 0.82 | ALDH1A1 (0.39) | GAAALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL30359485 | 0.76 | GAA (0.37) | GAAALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL2402204 | 0.76 | GAA (0.37) | GAAALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL20203935 | 0.68 | ALDH1A1 (0.36) | GAAALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL14431678 | 0.68 | CCR4 (0.35) | ALDH1A1CCR4ATR | |
| SCHEMBL25528098 | 0.68 | GAA (0.33) | GAAALDH1A1KMT2AKDM4EPOLB | |
| SCHEMBL29893180 | 0.67 | CCR4 (0.34) | CCR4 | |
| SCHEMBL2401931 | 0.67 | CCR4 (0.34) | CCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4433485-A1 | ADENOSINE RECEPTOR ANTAGONISTS | Crossignal Therapeutics, Inc. (US) | 2024-09-25 | — | — | EP | disclosed |
| EP-4313308-A1 | TEAD INHIBITORS AND USES THEREOF | Cedilla Therapeutics, Inc. (US) | 2024-02-07 | — | — | EP | disclosed |
| WO-2023091604-A1 | ADENOSINE RECEPTOR ANTAGONISTS | CROSSIGNAL THERAPEUTICS, INC. (US) | 2023-05-25 | — | — | WO | disclosed |
| WO-2022204452-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2022-09-29 | — | — | WO | disclosed |