Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 19/20 | 0.61 |
| ▸ | PDE2A | O00408 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28889157 | 1.00 | MAT2A (0.61) | MAT2APDE2APDE10A | |
| SCHEMBL28889355 | 0.92 | MAT2A (0.72) | MAT2A | |
| SCHEMBL29893876 | 0.92 | MAT2A (0.72) | MAT2A | |
| SCHEMBL28889327 | 0.90 | MAT2A (0.76) | MAT2A | |
| SCHEMBL29893675 | 0.90 | MAT2A (0.76) | MAT2A | |
| SCHEMBL28889320 | 0.89 | MAT2A (0.62) | MAT2A | |
| SCHEMBL28889344 | 0.89 | MAT2A (0.58) | MAT2A | |
| SCHEMBL29893617 | 0.89 | MAT2A (0.58) | MAT2A | |
| SCHEMBL24109548 | 0.89 | MAT2A (0.76) | MAT2A | |
| SCHEMBL28889309 | 0.88 | MAT2A (0.56) | MAT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022222911-A1 | PYRIMIDONE COMPOUND AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2022-10-27 | — | — | WO | disclosed |
| CN-115215862-A | Pyrimidone compounds and uses thereof | 武汉人福创新药物研发中心有限公司 | 2022-10-21 | — | — | CN | disclosed |