Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 19/20 | 0.59 |
| ▸ | BRD4 | O60885 | 2/20 | 0.58 |
| ▸ | DDB1 | Q16531 | 4/20 | 0.52 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23453409 | 1.00 | CRBN (0.59) | CRBNBRD4DDB1PARP1IKZF3 | |
| SCHEMBL23453408 | 0.94 | CRBN (0.52) | CRBNBRD4DDB1PARP1IKZF3 | |
| SCHEMBL30001032 | 0.94 | CRBN (0.52) | CRBNBRD4DDB1PARP1IKZF3 | |
| SCHEMBL31178061 | 0.89 | PARP1 (0.51) | CRBNBRD4DDB1PARP1 | |
| SCHEMBL23453406 | 0.89 | PARP1 (0.51) | CRBNBRD4DDB1PARP1 | |
| SCHEMBL23453398 | 0.87 | CRBN (0.58) | CRBNBRD4DDB1PARP1IKZF3 | |
| SCHEMBL31178048 | 0.87 | CRBN (0.58) | CRBNBRD4DDB1PARP1IKZF3 | |
| SCHEMBL23456486 | 0.85 | CRBN (0.50) | CRBNBRD4DDB1IKZF3 | |
| SCHEMBL23458427 | 0.85 | CRBN (0.53) | CRBNBRD4DDB1PARP1 | |
| SCHEMBL23453403 | 0.84 | CRBN (0.55) | CRBNBRD4DDB1IKZF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115023419-A | Cereblon-bound piperidine-2, 6-diones and methods of use thereof | 凯普托尔治疗学股份有限公司 | 2022-09-06 | — | — | CN | disclosed |