Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 4/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22143587 | 1.00 | AAK1 (0.37) | AAK1RIPK1BRD3MMP13CTSL | |
| SCHEMBL29894928 | 0.94 | AAK1 (0.38) | AAK1RIPK1MMP13CTSLKDM4D | |
| SCHEMBL24593526 | 0.94 | AAK1 (0.38) | AAK1RIPK1MMP13CTSLKDM4D | |
| SCHEMBL29894873 | 0.90 | AAK1 (0.42) | AAK1BRD3MMP13CTSLTRPA1 | |
| SCHEMBL22143615 | 0.90 | AAK1 (0.42) | AAK1BRD3MMP13CTSLTRPA1 | |
| SCHEMBL29895486 | 0.90 | AAK1 (0.42) | AAK1BRD3MMP13CTSLTRPA1 | |
| SCHEMBL22143582 | 0.90 | AAK1 (0.42) | AAK1BRD3MMP13CTSLTRPA1 | |
| SCHEMBL22143578 | 0.83 | AAK1 (0.43) | AAK1MMP13CTSLTRPA1IDO1 | |
| SCHEMBL24593697 | 0.83 | MMP13 (0.38) | AAK1BRD3MMP13KDM4DSCN9A | |
| SCHEMBL22143909 | 0.83 | AAK1 (0.43) | AAK1MMP13CTSLTRPA1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11377425-B1 | Small molecule modulators of IL-17 | LEO PHARMA A/S (DK) | 2022-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11377425-B1 | Small molecule modulators of IL-17 | IL17A, IL15, IL2 | AAK1 2606/4885RIPK1 2115/4885BRD3 511/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.