Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 10/20 | 0.47 |
| ▸ | LIPG | Q9Y5X9 | 10/20 | 0.47 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | ABL1 | P00519 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.37 |
| ▸ | SNCA | P37840 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9941723 | 1.00 | LPL (0.47) | LPLLIPGPDPK1IRAK4CA1 | |
| SCHEMBL19532044 | 0.94 | LPL (0.43) | LPLLIPGPDPK1IRAK4CA1 | |
| SCHEMBL1293460 | 0.82 | LPL (0.62) | LPLLIPGIRAK4CA1CA2 | |
| SCHEMBL29644319 | 0.82 | LPL (0.62) | LPLLIPGIRAK4CA1CA2 | |
| SCHEMBL7600427 | 0.79 | LPL (0.55) | LPLLIPGIRAK4SNCADGAT1 | |
| SCHEMBL101385 | 0.79 | LPL (0.53) | LPLLIPGIRAK4CA1CA2 | |
| SCHEMBL20967236 | 0.79 | PDGFRB (0.38) | LPLLIPGPDPK1SNCAPDGFRB | |
| SCHEMBL2708689 | 0.78 | LPL (0.59) | LPLLIPGIRAK4CA1CA2 | |
| SCHEMBL4299809 | 0.78 | LPL (0.59) | LPLLIPGIRAK4CA1CA2 | |
| SCHEMBL1344397 | 0.78 | KDR (0.43) | LPLLIPGIRAK4CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4051664-A1 | ISOQUINOLINE DERIVATIVES AS SIK2 INHIBITORS | Cancer Research Technology Limited (GB) | 2022-09-07 | — | — | EP | disclosed |