SCHEMBL29897699

SCHEMBL29897699

COc1cccc(C2=NC(c3cc(F)c(F)c(F)c3F)(C3(c4cc(F)c(F)c(F)c4F)N=C(c4cccc(OC)c4)C(c4cccc(OC)c4)=N3)N=C2c2cccc(OC)c2)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 1/20 0.41
CLK4 Q9HAZ1 1/20 0.41
ADORA2A P29274 2/20 0.40
ADORA1 P30542 1/20 0.40
HSD17B1 P14061 1/20 0.39
HSD17B2 P37059 1/20 0.39
KDM1A O60341 2/20 0.39
KDM1B Q8NB78 2/20 0.39
AKR1C3 P42330 2/20 0.38
AKR1C2 P52895 2/20 0.38
RPS6KA3 P51812 1/20 0.38
NPY5R Q15761 1/20 0.38
XDH P47989 1/20 0.37
BACE1 P56817 2/20 0.37
NPC1 O15118 1/20 0.37
POLB P06746 1/20 0.37
HTT P42858 1/20 0.37
RAB9A P51151 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
KCNH2 Q12809 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6935532 1.00 DYRK1A (0.41) DYRK1ACLK4ADORA2AADORA1HSD17B1
SCHEMBL6935907 0.89 ADORA2A (0.43) DYRK1ACLK4ADORA2AADORA1KDM1A
SCHEMBL29888758 0.89 ADORA2A (0.43) DYRK1ACLK4ADORA2AADORA1KDM1A
SCHEMBL29510931 0.88 DYRK1A (0.40) DYRK1ACLK4ADORA2AADORA1HSD17B1
SCHEMBL6941647 0.88 DYRK1A (0.40) DYRK1ACLK4ADORA2AADORA1HSD17B1
SCHEMBL6941966 0.86 DYRK1A (0.43) DYRK1ACLK4ADORA2AADORA1KDM1A
SCHEMBL29510957 0.86 DYRK1A (0.43) DYRK1ACLK4ADORA2AADORA1KDM1A
SCHEMBL6937881 0.85 DYRK1A (0.42) DYRK1ACLK4ADORA2AADORA1HSD17B1
SCHEMBL29508331 0.85 DYRK1A (0.42) DYRK1ACLK4ADORA2AADORA1HSD17B1
SCHEMBL30040209 0.84 DYRK1A (0.46) DYRK1ACLK4ADORA2AADORA1KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115524922-A Photosensitive resin composition 旭化成株式会社 2022-12-27 CN disclosed
CN-110325913-B Photosensitive resin composition 旭化成株式会社 2022-11-01 CN disclosed
WO-2022186389-A1 PHOTOSENSITIVE RESIN MULTILAYER BODY AND METHOD FOR PRODUCING SAME 旭化成株式会社 2022-09-09 WO disclosed