Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.61 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.61 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.61 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.55 |
| ▸ | KDM1A | O60341 | 3/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | KDM5A | P29375 | 1/20 | 0.47 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.47 |
| ▸ | REN | P00797 | 9/20 | 0.46 |
| ▸ | NPY1R | P25929 | 1/20 | 0.44 |
| ▸ | NPY2R | P49146 | 1/20 | 0.44 |
| ▸ | NPY4R | P50391 | 1/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30658576 | 0.88 | KDM1A (0.51) | MAPK8MAPK9MAPK10KEAP1KDM1A | |
| SCHEMBL30930547 | 0.86 | KDM1A (0.56) | MAPK8MAPK9MAPK10KEAP1KDM1A | |
| SCHEMBL3215690 | 0.86 | MAPK8 (0.51) | MAPK8MAPK9MAPK10KEAP1KDM1A | |
| SCHEMBL29680012 | 0.85 | MAPK8 (0.48) | MAPK8MAPK9MAPK10KEAP1REN | |
| SCHEMBL31462062 | 0.85 | MAPK8 (0.48) | MAPK8MAPK9MAPK10KDM1AMAOB | |
| SCHEMBL30686009 | 0.84 | MAPK8 (0.49) | MAPK8MAPK9MAPK10KEAP1REN | |
| SCHEMBL29611810 | 0.84 | MAPK8 (0.49) | MAPK8MAPK9MAPK10KEAP1 | |
| SCHEMBL29611735 | 0.84 | MAPK8 (0.53) | MAPK8MAPK9MAPK10NPY1RNPY2R | |
| SCHEMBL31410879 | 0.83 | NPY2R (0.47) | MAPK8MAPK9MAPK10KEAP1KDM1A | |
| SCHEMBL31410825 | 0.83 | MAPK8 (0.56) | MAPK8MAPK9MAPK10KEAP1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115028706-B | Application of Ma Rulao protein small molecule peptide in preparation of dipeptidyl peptidase IV inhibitor | 昆明理工大学 | 2024-02-09 | — | — | CN | claimed |
| CN-115028706-A | Application of fetoprotein small molecule peptide in preparation of dipeptidyl peptidase IV inhibitor | 昆明理工大学 | 2022-09-09 | — | — | CN | claimed |
| CN-115028706-B | Application of Ma Rulao protein small molecule peptide in preparation of dipeptidyl peptidase IV inhibitor | 昆明理工大学 | 2024-02-09 | — | — | CN | disclosed |
| CN-115028706-B | Application of Ma Rulao protein small molecule peptide in preparation of dipeptidyl peptidase IV inhibitor | 昆明理工大学 | 2024-02-09 | — | — | CN | disclosed |
| CN-115028706-A | Application of fetoprotein small molecule peptide in preparation of dipeptidyl peptidase IV inhibitor | 昆明理工大学 | 2022-09-09 | — | — | CN | disclosed |
| CN-115028706-A | Application of fetoprotein small molecule peptide in preparation of dipeptidyl peptidase IV inhibitor | 昆明理工大学 | 2022-09-09 | — | — | CN | disclosed |