Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.51 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.51 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.51 |
| ▸ | KDM1A | O60341 | 3/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | KDM5A | P29375 | 1/20 | 0.46 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.46 |
| ▸ | NMUR2 | Q9GZQ4 | 4/20 | 0.43 |
| ▸ | NMUR1 | Q9HB89 | 4/20 | 0.43 |
| ▸ | REN | P00797 | 5/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.41 |
| ▸ | GRB2 | P62993 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30658576 | 0.98 | KDM1A (0.51) | MAPK8MAPK9MAPK10KDM1AMAOB | |
| SCHEMBL31696335 | 0.96 | KDM1A (0.54) | MAPK8MAPK9MAPK10KDM1AMAOB | |
| SCHEMBL3865485 | 0.96 | MAPK8 (0.50) | MAPK8MAPK9MAPK10KDM1AMAOB | |
| SCHEMBL29548952 | 0.94 | KDM1A (0.48) | MAPK8MAPK9MAPK10KDM1AMAOB | |
| SCHEMBL30844390 | 0.92 | MAPK8 (0.54) | MAPK8MAPK9MAPK10KDM1AMAOB | |
| SCHEMBL31031628 | 0.92 | MAPK8 (0.47) | MAPK8MAPK9MAPK10KDM1AMAOB | |
| SCHEMBL31696260 | 0.91 | GRB2 (0.44) | MAPK8MAPK9MAPK10KDM1AMAOB | |
| SCHEMBL30844398 | 0.90 | MAPK8 (0.54) | MAPK8MAPK9MAPK10KDM1AMAOB | |
| SCHEMBL30381351 | 0.89 | KDM1A (0.57) | MAPK8MAPK9MAPK10KDM1AMAOB | |
| SCHEMBL30522782 | 0.89 | MEN1 (0.41) | MAPK8MAPK9MAPK10KDM1AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8962697-B2 | Bioreponsive polymers | INTERFACE BIOLOGICS INC. (CA) | 2015-02-24 | — | — | US | disclosed |
| US-20100041771-A1 | Bioreponsive Polymers | INTERFACE BIOLOGICS, INC. | 2010-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041771-A1 | Bioreponsive Polymers | PEPD, PREP, DNPEP | MAPK8 1973/4885MAPK9 2837/4885MAPK10 3721/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.