Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK7 | P50613 | 18/20 | 0.48 |
| ▸ | CDK2 | P24941 | 10/20 | 0.46 |
| ▸ | CCNE1 | P24864 | 8/20 | 0.46 |
| ▸ | CCNH | P51946 | 8/20 | 0.46 |
| ▸ | CDK1 | P06493 | 7/20 | 0.46 |
| ▸ | MNAT1 | P51948 | 7/20 | 0.46 |
| ▸ | CDK9 | P50750 | 5/20 | 0.46 |
| ▸ | CDK4 | P11802 | 4/20 | 0.46 |
| ▸ | CDK6 | Q00534 | 4/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.46 |
| ▸ | CDK8 | P49336 | 3/20 | 0.46 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.46 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.46 |
| ▸ | CCND1 | P24385 | 2/20 | 0.46 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.46 |
| ▸ | INSRR | P14616 | 1/20 | 0.45 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23530960 | 1.00 | CDK7 (0.48) | CDK7CDK2CCNE1CCNHCDK1 | |
| SCHEMBL21486446 | 0.84 | CDK7 (0.46) | CDK7CDK2CCNE1CCNHCDK1 | |
| SCHEMBL33378025 | 0.83 | KDM4E (0.56) | CDK7CDK2CCNE1CCNHCDK1 | |
| SCHEMBL24963255 | 0.82 | CDK7 (0.42) | CDK7CDK2CCNE1CCNHCDK1 | |
| SCHEMBL30209126 | 0.82 | CDK7 (0.42) | CDK7CDK2CCNE1CCNHCDK1 | |
| SCHEMBL30209128 | 0.82 | CDK7 (0.42) | CDK7CDK2CCNE1CCNHCDK1 | |
| SCHEMBL23530989 | 0.82 | CDK7 (0.52) | CDK7CDK2CCNE1CCNHCDK1 | |
| SCHEMBL1370667 | 0.82 | CDK7 (0.66) | CDK7CDK2CCNE1CCNHCDK1 | |
| SCHEMBL24962532 | 0.80 | CDK7 (0.51) | CDK7CDK2CCNE1CCNHCDK1 | |
| SCHEMBL33378043 | 0.80 | CDK7 (0.46) | CDK7CDK2CCNE1CCNHCDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114929708-B | 4- [ [ (7-Aminopyrazolo [1,5-a ] pyrimidin-5-yl) amino ] methyl ] piperidin-3-ol compounds and their therapeutic uses | 卡里克治疗有限公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-114929708-A | 4- [ [ (7-aminopyrazolo [1,5-A ] pyrimidin-5-yl) amino ] methyl ] piperidin-3-ol compounds and their therapeutic use | 卡里克治疗有限公司 | 2022-08-19 | — | — | CN | disclosed |